The purposes of the study:
1.Establishing of population frequency of HR HPV infection was the main purpose of the study concerning cervical carcinoma screening program.
2. Logistics for co-test (cytology and HR HPV test) implementation in Poland.
The study covered unselected 10112 women age 30-59 years old, including 3089 from urban and 7023 from rural area. All samples were genotyped with Abbott High-Risk HPV Real –time PCR on automated platform Abbott M2000. Conventional Pap tests were performed the same time.
In the studied population generally there were 6,6% positive tests for HR HPV (7,5% in urban area and 4,9% in rural population). Among positive cases type HPV16 prevailed followed by type 18. Percentage of HR HPV positive cases was decreasing with age.
Correlation of HR HPV test results with cytological reports revealed that only in 27% HR HPV positive cases cytological abnormality (LGSIL, ASCUS, ASCUS-H, HGSIL) were found.
The percentage of HR HPV case in Poland was relatively low, especially in rural population. The project allowed preparing introduction of co-test in national prophylactic program for cervical carcinoma.