The goal of this study is to analyse the accuracy of cytologic and colposcopic findings and compare it with the results of histology by LEEP or Fisher conisation.
Material of clinical studies of 230 patients with cervical pathology has been analysed.
They were assigned to treatment by Fisher cone biopsy excisor or other excisional methods of the cervix.
Eligibility criteria included CIN 2 or 3 detected by punch biopsy or discrepations between cytology, biopsy and colposcopy examination or long time persistent CIN1.
A pathologist analysed the degree of neoplasia, specimens for margin interpretability and adequacy of excision as well as HPV testing.
LEEP method have some disadvantages, included electrocautery artifacts or fragment pieces. That leaded to difficulties with safety evaluations of gained margins.
Specimens with interpretable margins were in 94% of all cases. In 6% of cases we found out recurrence of CIN and in 4% cases CIS of the cervix, in some cases in the endocervical location.
No problems in course of next pregnancy in the cases of Fisher cone biopsy were observed
Method of Fisher conisation appears to be a safe and reliable method for diagnosis, treatment and thrifty towards next pregnancy possibility.