There is accumulating evidence that HPV-transformed keratinocytes actively contribute to the inflammatory microenvironment during cervical carcinogenesis promoting the progression from high-grade precursor lesions to invasive cancer.
This lecture will give an overview on inflammatory immune responses in cervical high-grade lesions and invasive cervical cancer.
This lecture will provide detailed information on molecular mechanisms underlying inflammatory responses in HPV-driven carcinogenesis and potential consequences for targeted immunotherapies.
Understanding the immune microenvironment in HPV-associated carcinogenesis is important for the design of novel immunotherapies.