Recurrent respiratory papillomas can be a devastating consequence of HPV infection in the upper aerodigestive tract. Surgical treatments have been more paliative than curative. This talk will review the current state-of-the-art in terms of surgical and adjuvant medical therapies in children and adults.
A comprehensive review of the current literature in combination with personal experiences in management of difficult cases.
Results from case series and expert opinions will be presented with respect to the use of Cidofovir, Avastin, Celebrex and interferons. Ongoing trials will also be discussed.
The search for a "cure" continues to treat this vexing disease. The greatest optimism lies in prevention through vaccination.
Derkay CS, Wiatrak B. Recurrent Respiratory Papillomatosis: A Review. Laryngoscope. 2008; 118: 1236–1247.
Schraff S, Derkay CS, Burke B, Lawson L. American Society of Pediatric Otolaryngology members' experience with recurrent respiratory papillomatosis and the use of adjuvant therapy. Arch Otolaryngol Head Neck Surg. 2004; 130: 1039-1042
Chadha NK, James A. Adjuvant antiviral therapy for recurrent respiratory papillomatosis. Cochrane Database of Systematic Reviews. 2010; (1):CD005053.