Turkey has implemented HPv DNA Testing as a primary screening tool by 2013. This abstract aims to update the current results of screening with initial colposcopy and histology results.
Women age 30 years and older are invited for cervical cancer screening. All ladies are sampled for via HPV DNA and conventional cytology. Target population totally for 5 years was 15 million. All samples wer collected in a central Mega HPV lab in Ankara. For HPV positive cases, additional HPV Genotyping plus cytological evaluations are done. HPV DNA is analysed by HC2, genotyings were done using Genomica kits.
Among evaluated 2 million ladies, HPV positivity rate was 3,8%. The most common type for HPV was 16, followed by 51, 31. Among these cases, most common histological abnormalities were LSIL followed by ASC-US and H-SIL. Most common type of colposcopic procedures were punch biopsy. Among screened group, highest peak age of HPV positivity and cytological abnormalities was seen between 35-30. Among all colposcopic biopsies, a great majority of the cases detected were CIN3 (15%), followed by CIN2 and CIN1. Invasive cervical cancer incidence was more than 30/ 100.000 among screened population compared to 4/ 100.000 in general Turkish population.
HPV DNA Tests are feasible to apply to general population. Turkey is the first to impelemet this natioanally in a large population for over 15 million ladies. This presentation gives the preliminary results of a nation wide screening.