Evaluation of consistency of the final histopathological diagnosis following diagnostic and therapeutic process of leep conization till the primary histopathological diagnosis following targeted cervical biopsy.
The analysis included 540 patients, in whom leep conization was performed due to incorrect result following targeted biopsy – SIL or discrepancy of cytological – histopathological results.Targeted biopsy and leep conization were performed by doctors with years of experience. Colposcopy was performed using stereoscopic colposcope (Olympus OCS-500). Colposcopic pictures were evaluated according to Reid’s index, regarding the margin and acetowhitening, iodine negative test and vascularization.
The most frequent histopathological diagnosis following targeted biopsy and leep conization were HGSIL-CIN 2 type changes, which comprised 36% and 34% respectively and HGSIL-CIN 3 type changes which comprised 21% and 27% respectively. Conistency of histopathological results of targeted biopsy compared to the final result following leep conization comprised 94% for HGSIL type changes.
Targeted cervical biopsy and leep conization show very high consistency in terms of histopathological results.