FC 19-01AGE DISTRIBUTION AND PROBABILITY OF HYSTERECTOMY IN GERMANY

36. Public health
S. Schülein 1, O. Schoffer 1, K. Radde 1, J. König 2, V. Weyer 2, M. Blettner 2, S. Klug 1.
1Epidemiology, Department of Sport and Health Sciences, Technical University of Munich, Georg-Brauchle Ring 56, 80992 Munich (Germany), 2Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg University, Obere Zahlbacher Straße 69, 55131 Mainz (Germany)

Background / Objectives

Hysterectomy is the most common gynecological surgery in many industrialized countries. In Germany, the hysterectomy rate is high in comparison to other European countries. The aim of this analysis was to determine the distribution of age at hysterectomy as well as the age-specific probability of undergoing a hysterectomy between the ages of 0-64 in the German female population.


Methods

Analyses were based on data from the MARZY study, a prospective, randomized, population-based cohort study investigating early detection of cervical cancer in western Germany. At baseline, 6 429 women were invited to attend cervical cancer screening. The distribution of age at hysterectomy as well as indications for hysterectomy were reported. Based on survival analysis, which accounts for censoring at the age of interview, and the inverse probability weighting (IPW) method, the age-specific probability of undergoing a hysterectomy was estimated. The IPW method corrected for missing date of hysterecomy. Simulated calendar-period specific survival curves (1939-1979, 1980-1989, 1990-1999, 2000-2006) were computed to show how age and calendar year determine the probability of undergoing a hysterectomy.


Results

Data on hysterectomy were available for 4 719 women. Of these, 961 women (20.4%) had undergone a hysterectomy. The main indication for hysterectomy was uterine fibroids (48%). A total of 850 women (88.4%) reported a date when their hysterectomy had been performed. The highest proportion of women were hysterectomized between the ages of 40-44 (24.6%). The IPW corrected probability of having a hysterectomy between the ages of 0-64 was 0.354. The age-specific probability of hysterectomy was highest in the 45-49 year age group (0.078). The age-specific probability of hysterectomy decreased between the years 1939 to 2006.


Conclusion

Data from the MARZY study allowed valuable conclusions to be drawn about the distribution of age at hysterectomy as well as the age-specific probability of undergoing a hysterectomy in Germany.


References