To explore the epidemiologic characteristics of human papillomavirus (HPV) infection among women from Jungar banner , Inner Mongolia, China, and analyze the related risk factors .
The cervical cancer screening program for women aged 35-64 has been conducted in Jungar banner , Inner Mongolia, China in 2016. CareHPV was applied as primary screening method followed by visual inspection with acetic acid/Lugol’s iodine（VIA/VILI）as triage method. The HPV and VIA/VILI positive women were referred to colposcopy and biopsy if necessary. Chi-square and stepwise logistic regression analysis were performed by using the SPSS21.0 statistical software.
A total of 7659 women received careHPV test were included in the final analysis. Average age of the study population was（45.55±7.37）years. The overall HPV infection rate was14.60%, and there was no difference between Han and the Mongol nationality with the infection rates of 14.54% and 15.26%, respectively (P > 0.05). The HPV infection rates in ≤CIN1(normal or cervical intraepithelial neoplasia grade 1) and CIN2+( cervical intraepithelial neoplasia grade 2 or higher) were 14.14%、and 82.98%，P=0.00; The HPV infection rates were different among the different age groups：13.71%（≤44years old）、14.26%（45~54years old）、18.74%(≥55years old), （χ2=15.93，P=0.00）. Single factor logistic regression analysis shows that the age of sexual debut（≤20years old, with OR=1.45 ,95％C1:1.23-1.72）, the first childbirth age(<25years old, with OR=1.21 ,95％C1:1.04-1.39), unmarried（OR=1.76, 95％C1:1.05-2.95）, education levels at high school and below(OR=1.43, 95％C1：1.18-1.74), the history of reproductive diseases(OR=1.29, 95％C1:1.11-1.49)and multiple parity(>2 times with OR=1.23, 95％C1:1.02-1.47）would increase the Han's risk of HPV infection . However, only the first childbirth age（<25years old）was significantly related with HPV infection in Mongol women with OR=1.60 ,95％C1:1.01-2.52. Multi factor unconditional logistic regression revealed that the age of sexual debut , marital status, the history of reproductive diseases were significantly connected with HPV infection.
The overall HPV infection rate of women in Inner Mongolia was higher than that in rural areas of China. HPV positivity among women with CINII+ was significantly higher than that among women with normal cervix or CINI. Risk factors of HPV infection were different between Han and the Mongol nationality; Cervical cancer prevention propaganda should be strengthened to reduce the disease burden of cervical cancer.