| Wednesday, June 28th - Cell death pathways and onco-pharmacology |
| 09h30 |
Registration opening - Notice: ID will be required. |
| Session 1 - Chairman and chairwoman: Guido Kroemer & Marie-Lise Gougeon |
| 10h00 |
Opening |
| 10h10 |
Keynote Mauro Piacentini - University of Rome "Tor Vergata" - "The role of Type 2 Transglutaminase in Hepatocarcinogenesis." |
| 10h50 |
Coffee Break |
| Session 2 - Chairwoman: Inna Lavrik |
| 11h20 |
Georg Häcker - University of Freiburg Medical Center, Institute for Microbiology and Hygiene - "Sub-lethal signaling in the mitochondrial apoptosis pathway" |
| 11h45 |
Inna Lavrik - Medical Faculty, University of Magdeburg, OVGU - "Targeting extrinsic apoptosis network in cancer cells" |
| 12h10 |
Lunch break & Poster session A |
| Session 3 - Chairman : Gerry Melino |
| 13h30 |
J.Marie Hardwick - Johns Hopkins University - CDD Award 2022 lecture - "Cell death is intrinsic to life - including microorganisms" |
| 14h10 |
Gerry Melino - University Rome Tor Vergata - "Distinct mechanisms regulating p63 function" |
| 14h35 |
Daolin Tang - UTSW - "A novel ferroptosis-inducing strategy to enhance anti-tumor immunity" |
| 15h00 |
Pier Giuseppe Pelicci - European Institute of Oncology - "Non-genetic mechanisms of cancer treatment resistance" |
| 15h25 |
Lígia Gomes-da-Silva - Universidade de Coimbra - "Photodymanic therapy and its immunoadjuvant properties for cancer treatment" |
| 15h50 |
Presentation of ECDO conference 2024 |
| 16h05 |
Coffee Break |
| Session 4 - Chairman : Mauro Piacentini |
| 16h35 |
Kevin Ryan - Cancer research UK Beatson Institute - "Connecting Autophagy and Inflammation to Regulate Programmed Cell Death" |
| 17h00 |
3 selected abstracts
"Uncovering nuclear expulsion, chromatin-bound signals from dying cancer cells accelerate metastatic outgrowth" - L.Yang
"Direct and specific interaction of C-terminal transmembrane domains of Bcl-2 family proteins revealed by a split luciferase assay" - F.Essmann
"Regulation of lysosomal integrity and function by DNA ligands in cancer cells" - L.Ferret
|
| 18h00 |
Charles Swanton - ECDO Prize & CDD Award 2023 lecture - "Mechanism of Action and Inflammatory Axis for Air Pollution Induced Non-Small Cell Lung Cancer" - REMOTE; |
| 18h40-18h55 |
ECDO General Assembly |
| 19h00 - 20h30 |
WELCOME RECEPTION |
| Thursday, June 29th - Immunogenic cancer cell death |
| Session 1 - Chairwoman : Patrizia Agostinis |
| 09h30 |
Keynote Patrizia Agostinis - Center for Cancer Biology (CCB) -VIB / KU Leuven - "Deploying T cell recruitment tactics to overcome cancer immune evasion." |
| 10h10 |
Alberto Bardelli - IFOM - “Exploiting immune surveillance to target colorectal cancer evolution and mutability” |
| 10h35 |
Jitka Fucikova - Charles University and SOTIO Biotech - "The clinical relevance of immunogenic cell death in cancer therapy" |
| 11h00 |
Coffee Break |
| Session 2 - Chairman : Boris Zhivotovsky |
| 11h30 |
Lorenzo Galluzzi - Weill Cornell Medicine - "Cellular mechanisms underlying the immunogenicity of RT in clinically relevant oncological settings" |
| 11h55 |
Oliver Kepp - INSERM - "Immunogenic cell death enhancers for cancer therapy" |
| 12h20 |
Lunch Break & Poster session B |
| 12h20-13h20 |
ECDO Board Meeting |
| Session 3 - Chairman : Peter Krammer |
| 14h00 |
François Ghiringhelli - INSERM - Bourgogne Univeristy - "IL-1 to overcome resistance to chemoimmunotherapy" |
| 14h25 |
Evangelos Giampazolias - Cancer Research UK Manchester Institute - "Decoding host-microbiome interactions that regulate cancer immunity. Killing cancer with a gut instinct." |
| 14h50 |
Eric Vivier - Innate Pharma - "Harnessing NK cells in cancer therapies" |
| 15h15 |
3 selected abstracts
"Plasma CD27, a surrogate of the intratumoral CD27-CD70 interaction, correlates with immunotherapy resistance in renal cell carcinoma" - I.Sam
"GABARAP loss is a novel mechanism of tumor resistance to immunogenic chemotherapy in multiple myeloma" - A.Gullà
"Harnessing the immunogenic properties of senescent cells in cancer therapy" - F.Pietrocola
|
| 16h15 |
Coffee Break |
| Session 4 - Chairman : Peter Vandenabeele |
| 16h45 |
Peter Vandenabeele - VIB - UGENT - "How does ferroptosis prevent antigen cross presentation during prophylactic cancer vaccination?" |
| 17h10 |
Zuzana Tatarova - Brigham and Women's Hospital, Harvard Medical School - "Longitudinal spatial analysis of immunogenic cell death in breast cancer" - REMOTE |
| 17h35 |
Antonella Sistigu - Università Cattolica del Sacro Cuore - "IFN-I-triggered epigenetic reprogramming. KDM1b at the forefront of tumor progression and immune evasion" |
| 18h00 |
Yuting Ma - Institute of Systems Medicine, Chinese Academy of Medical Sciences - "Multi-level stress and immune regulation" |
| 18h25-19h05 |
Manolis Pasparakis CDD Jürg Tschopp Prize 2023 lecture - University of Cologne - "RIPK1 and its role in cell death and inflammation" |
| 19h30 - 20h30 |
BOARDING GALA DINNER - PIER 4 - BADGE NEEDED |
| Friday, June 30th - Immuno-oncology |
| Session 1 - Chairman : Ignacio Melero |
| 09h00 |
Keynote Ignacio Melero - Universidad de Navarra Clinic / Cima Universidad de Navarra - "On the protumoral effects IL-8 and neutrophil extracellular traps." |
| 09h40 |
Hervé Fridman - Cordeliers Research Centre - "Generation of B cell immunity in Tertiary Lymphoid Structures supports response to immunotherapy" |
| 10h05 |
Miriam Merad - Icahn School of Medicine New York - "Targeting myeloid cells in cancer" |
| 10h30 |
Coffee Break |
| Session 2 - Chairman : Hervé Fridman |
| 11h00 |
Philipp Beckhove - Leibniz Institute for Immunotherapy (LIT) - "Salt-inducible kinase 3 protects pancreatic tumor cells from cytotoxic T-cell attack by promoting TNF-induced NF-κB activation" |
| 11h25 |
Alexander Eggermont - University Medical Center Utrecht - "The current revolution of NEOadjuvant IO in Melanoma and across multiple tumor types leads to More Cures, Shorter Treatments and Less Surgery" |
| 11h50 |
Lunch & Poster session C - CDD editorial board meeting |
| Session 3 - Chairman : Oliver Kepp |
| 13h30 |
Symposium 10x Genomics - Explore new pathways in cancer biology with Visium CytAssist and Xenium in situ platforms - Johanna Stergiadou - Science & Technology Advisor |
| 14h30 |
Sergio Abrignani - Fondazione INGM - University of Milan - "Functional interrogation of clonally expanded intratumoral T lymphocytes" |
| 14h55 |
Sebastian Kobold - Klinikum der Universität München - "Use of single cell analysis to guide cell therapy development" |
| 15h20 |
3 selected abstracts
"Co-targeting autophagy, macrophages and vasculature in glioma tumors triggers immunogenicity" - A.Chryplewicz
"UPR activation in cancer cells promotes anti-cancer immune response through DPM1-dependent control of PD-L1 glycosylation." - H.Issaoui
"Involvement of autoantibodies and B cell subsets in immune-related adverse events following immune checkpoint inhibitors therapy of melanoma patients" - S.Soussan
|
| 16h20 |
Coffee Break |
| Session 4 - Chairwoman : Laurence Zitvogel |
| 16h50 |
Peng Liu - INSERM - "Genetic Exploration of Cancer-Relevant Dendritic Cell Functions" |
| 17h15 |
Laurence Zitvogel |
| 17h40 |
Tadatsugu Taniguchi - Professor Emeritus, University of Tokyo Fellow / Research Center for Advanced Science and Technology, University of Tokyo - "Special closing lecture: Interferons, IRFs and DAMPs discovering the underpinnings of immunity: Gradus ad Parnassum in immunology" |
| Closing - Chairman and chairwoman : Guido Kroemer & Marie-Lise Gougeon |
| 18h25-18h35 |
Best Poster Award & Closing |
|