Microbiome analysis: are we ready for clinical use?
Tuesday, December 4, 2018
Scientific Session
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SS 07
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3:30 PM
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5:15 PM
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Microbiome analysis: are we ready for clinical use?
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Auditorium II
(Session supported by Procare Health)
Studies dating back several decades showed an association between bacterial vaginosis and the development of CIN. Bacterial vaginosis, which is a clinical diagnosis, is hallmarked by changes observed in the vaginal microbiome. With the recent discovery of ‘omics, the enormous complexity of the vaginal microbiome is being uncovered. Certainly, variations of the microbiome has been shown both between women and within a women. For example, some women have very diverse microbiomes with a combination of aerobic and anaerobic bacteria through-out the menstrual cycle whereas other women have very consistent Lactobacillus dominant microbiomes throught-out with extreme changes only during the menstrual cycle. Several studies now link the microbiome and its metabolic products with HPV persistence and CIN development. These rich data sets are moving into more translational science towards identifying signatures (whether microbiome, or metabonomics) that are associated with CIN development and into therapies aimed at restoring a more protective vaginal microbiome preventing and /or clearance of HPV. This session will examine aspects of these complex associations and potential biomarkers and therapies.
3:30 PM
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SS 07-01
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Variation of vaginal microbiome in women
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P.
Pekka
NIEMINEN
3:45 PM
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SS 07-02
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HPV persistence and clearance related to microbiota
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A-B.
Anna-Barbara
MOSCICKI
4:00 PM
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SS 07-03
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Role of vaginal microbiome in women with CIN
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M.
Maria
KYRGIOU
4:15 PM
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SS 07-04
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Temporal correlations of microbiome and cervical immune microenvironment
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P.
Patti
GRAVITT
4:30 PM
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SS 07-05
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Vaginal microbiome, metabonomics and biomarkers
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A.
Anita
MITRA
4:45 PM
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SS 07-06
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Effect of a coriolus versicolor-based vaginal gel in high-risk HPV infected patients. Results of different studies
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D.
Damián
Dexeus
5:00 PM
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SS 07-07
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Discussion
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