Triage markers for HPV-positive women: long term performance
Monday, December 3, 2018
Main Scientific Session
•
MSS 03
•
2:15 PM
>
3:45 PM
•
Triage markers for HPV-positive women: long term performance
•
Auditorium I
The move to primary cervical screening based on molecular HR-HPV testing demands optimal and efficient triage tests to support the risk stratification of those that warrant follow up from those who can be returned to routine screening . While there is established international consensus that HR-HPV testing is the optimal method of primary screening, there is considerable heterogeneity of approach with respect to triage strategies both in relation to the type of test - and the nature of the follow up protocol that the result indicates. Cytology and limited HPV genotyping are the most evidenced triage strategies so far however, other options designed to delineate transforming HPV infection also show promise including markers of aberrant viral life cycle, cell cycling and methylation. In this session the performance of established and emerging triage strategies will be discussed as will some of the challenges of implementation, including application to self taken samples. Additionally, considerations into how modelling can help to inform optimal strategies for triage will be discussed.
2:15 PM
•
MSS 03-01
•
Cytology
>
M.
Marc
ARBYN
2:26 PM
•
MSS 03-02
•
p16 or p16/Ki67
>
F.
Francesca
Carozzi
2:37 PM
•
MSS 03-03
•
Genotyping
>
N.
Nicolas
WENTZENSEN
2:48 PM
•
MSS 03-04
•
Methylation
>
C.
Chris
MEIJER
2:59 PM
•
MSS 03-05
•
E6-E7
>
A.
Andreas
KAUFMANN
3:10 PM
•
MSS 03-06
•
Triage using self-taken samples
>
D.
Daniëlle
HEIDEMAN
3:21 PM
•
MSS 03-07
•
What modelers tell us
>
H.
Hans
BERKHOF
3:32 PM
•
MSS 03-08
•
Discussion
|