E-poster - Red Cell Immunology: Serology

E-poster, E-poster
IMMUNOBIOLOGY EP-5.1 > E-poster - Red Cell Immunology: Serology E-poster IMMUNOBIOLOGY

P-449 ANTI-RH5 ALLOIMMUNIZATION IN INDIVIDUALS HARBORING A RN HAPLOTYPE: THE NEED TO ACKNOWLEDGE THAT THE RHCE*CERN VARIANT ALLELE ALSO ENCODES A PARTIAL LITTLE E (RH5) ANTIGEN > V. Vincent THONIER P-450 AN ANTIBODY AGAINST A NOVEL HIGH PREVALENCE ANTIGEN IN THE JMH BLOOD GROUP SYSTEM > C. Christine HENNY
Objectives : We report the case of a patient whose cells appear to lack a novel high prevalence antigen of the JMH system and the plasma contains the corresponding anti-JMH antibody.
Sequencing of SEMA7A revealed a homozygous missense substitution c.556G>A (p.Glu186Lys).
This novel antigen may become the eighth antigen of the JMH system upon successful ratification by the ISBT Working Party on Red Cell Immunogenetics and Blood Group Terminology.

P-451 THE FIRST REPORTED CASE OF AN ACUTE HEMOLYTIC TRANSFUSION REACTION DUE TO THE RARE SPECIFICITY ANTI-HUT (ANTI-MNS19) > R. Randall Velliquette P-452 TOWARDS AN APPROACH TO DETECT ANTI-IDIOTYPIC ANTIBODIES IN THE PLASMA OF AN ANTI-D DONOR, TO INVESTIGATE ANTIBODY-MEDIATED IMMUNOSUPPRESSION MECHANISMS ASSOCIATED WITH THE D ANTIGEN > E. Eunike (Nysa) MCGOWAN
Objectives : - anti-idiotypes (antibodies against other antibodies) have previously been found to be immunomodulatory
- antibodies to anti-D may be in the plasma of anti-D donors and contribute to efficacy of RhD-immunoglobulin
- promising progress has been made but further work is required to confirm validity of positive reactions
P-454 ANALYSIS OF TITRE SCORE AS A VALID ALTERNATIVE TO CONTINUOUS FLOW ANALYSIS FOR THE PREDICTION OF THE NATURE OF ANTI-D IN PREGNANCY > K. Kerry DOWLING
Objectives : I have no conflicts of interest
My name is Kerry Dowling, I am the Transfusion Laboratory Manager at University Hospitals Southampton NHS Foundation Trust and the deputy chair of the National Laboratory Managers Committee. I have completed this study with listed colleagues across the UK
P-455 RED CELL ALLOIMMUNIZATION IN HEMATO-ONCOLOGY PATIENTS TRANSFUSED WITH EXTENDED PHENOTYPE MATCHED PACKED RED BLOOD CELLS VERSUS THE ROUTINELY CROSSMATCHED UNITS > A. Ashish JAIN P-456 RH ANTIBODIES AS A RESULT OF ALTERED RH EPITOPES ON DONOR RED CELLS IN BRAZILIAN PATIENTS RECEIVING CHRONIC TRANSFUSIONS > L. Lilian CASTILHO
Objectives : The high frequency of altered RH alleles contribute to the high rate of alloimmunization in chronically transfused patients
Many Rh epitopes are involved in a small number of patients who develop unexplained Rh antibodies
Unexplained rh antibodies in transfused patients carrying conventional Rh antigens can be a result of TBC transfusions from donors with altered Rh epitopes
P-457 CASE REPORT: LIFE SAVING INCOMPATIBLE TRANSFUSION > Y-L. Young-Lan SONG
Objectives : Clinical significant antibodies can cause hemolytic transfusion reactions and have to be considered when transfusion is required.
Under special circumstances when compatible blood is not available only enzyme reactive antibodies might be neglected.
Cross matching is important to detect low prevalence antibodies.
P-458 CD47 EXPRESSION IN RBC OF DIFFERENT AGES > M. Maria ENSINCK P-459 CLINICAL LEARNING OUTCOMES FROM EXTERNAL QUALITY ASSESSMENT (EQA) OF POINT OF CARE TESTING FOR D TYPING (POCTD) – A UNITED KINGDOM NATIONAL EXTERNAL QUALITY ASSESSMENT SCHEME (UK NEQAS) > C. Claire WHITHAM
Objectives : To compare and contrast D typing in two differing key clinical testing settings.
To compare the error rates of D typing (false negative or false positive) between both clinical testing settings.
To assess the risks of making errors during testing, in light of the clinical context.
P-460 RETROSPECTIVE COHORT STUDY OF PATIENTS IN ENGLAND ON ANTI-CD38 THERAPEUTIC MONOCLONAL ANTIBODY (TMAB) THERAPIES > T. Tom BULLOCK P-461 ERYPTOSIS IN AUTOIMMUNE HEMOLYTIC ANEMIA RELATED TO IGM AUTOANTIBODIES DEPENDS ON SUBLYTIC TERMINAL COMPLEMENT COMPONENTS AND REPRESENTS A NEW DEGRADATION PATHWAY > T. Thilo BARTOLMAES P-462 STRATEGY FOR WEAK D GENOTYPING IN WOMEN UNDER FORTY-FIVE YEARS > S. Susana TUR CERVANTES P-463 THE QUINQUAGENARY OF INDIGENOUS OF INDIGENOUS AUSTRALIANS BLOOD GROUP PROFILES > A. Aoibhe MULCAHY
Objectives : - Blood group proflies of the First Nation peoples of Australia
- How next generation sequencing can enable a better understanding of culturally and linguistically diverse groups
- How transfusion medicine for Indigenous peoples can be improved
P-464 ANTIBODY SCREENING USING LASER INCUBATION > H. Heather MCLIESH P-465 ABO TITRATION PRECISION: MULTI-LABORATORY COMPARISON OF AUTOMATED ABO TITRATION ASSAYS WITH MANUAL COLUMN AGGLUTION TEST FOR BOTH IGG AND IGM ANTIBODIES > M. Michael SPIGARELLI P-466 Β-LACTAM ANTIBIOTICS PROMOTE AGING AND CLEARANCE OF RED BLOOD CELLS WOULD DETERIORATE THE DIIHA > Q. Qixiu YANG
Objectives : drug induced immune hemolytic anemia, RBC aging and clearance, antibiotics
P-467 RED CELL PHENOTYPING AND GENOTYPING AUSTRALIAN BLOOD DONORS > T. Tanya POWLEY
Objectives : Increasing demand for phenotyped red cells
Phenotyping and genotyping strategies to meet demand
The use of mathematical modelling to inform strategies
P-468 ANALYSIS ON ABO TYPING DISCREPANCIES AMONG PATIENTS IN A TERTIARY CARE HOSPITAL > W. Wonyoung HEO P-469 A RETROSPECTIVE STUDY ON D VARIANT PHENOTYPES IN HONG KONG BLOOD DONORS > J. John NG
Objectives : I would like to declare there is no conflict of interests in this presentation.
P-471 STUDY ON THE PREVALENCE AND SEROLOGICAL DISTRIBUTION CHARACTERISTICS OF WEAK ABO SUBGROUPS IN A CHINESE POPULATION > Z. Zhongying WANG P-473 AUTOMATED ALLOANTIBODY TITRATION ASSAYS: TITER RESULT CONSISTENCY > A. Alina GELLERER
Objectives : Immucor developed a set of fully automated alloantibody titration assays on the NEO Iris platform.

The automated alloantibody titration assays demonstrate a high titer consistency in internal and external validation.

High titer consistency and minimum hands-on time are an advantage of the automated alloantibody titration assays as compared to manual methods.
P-474 ANTI-A AND ANTI-B WITH CRITICAL IGM AND IGG TITERS OF 64 CORRELATE TO SAFE ABO-MINOR INCOMPATIBLE PLATELET TRANSFUSION PRACTICE > C. Carolina BUB
Objectives : no conflict of interests
P-475 THE DITHIOTHREITOL (DTT) METHOD TO MANAGE DARATUMUMAB INTERFERENCE: DETECTION OF ANTI-K > N. Nazia Lone AKHTAR
Objectives : The aim was to evaluate the effect of the concentration dependent DTT treatment of red blood cells on the ability to detect anti-K antibodies of various strength.
P-477 NOT ALL RED BLOOD CELLS ARE REACTIVE WITH ANTI-CD38 IGG IN THE INDIRECT ANTIGLOBULIN TEST: CORRELATION WITH BLOOD GROUP PHENOTYPES > P. Peter SCHWIND
Objectives : CD38 status of Reagent Red Blood Cells
Use of a therapeutic drug as Blood Group Phenotyping Reagent
Information on Antigen Tables of RRBC manufacturers
P-478 DEVELOPMENT AND EXECUTION OF A STRATEGY FOR THE VALIDATION AND IMPLEMENTATION OF THE OLYMPUS PK7400 PLATFORM FOR BLOOD GROUP AND TPHA TESTING OF BLOOD DONATIONS > A. Anton VAN WEERT P-479 RED CELL ALLOIMMUNIZATION IN MULTITRANSFUSED ONCOLOGY PATIENTS AT A TEACHING HOSPITAL IN LAHORE, PAKISTAN > A. Aisha MAHESAR P-480 IRREGULAR ANTIBODIES IN THE GEL CARD ERA: 16 – YEAR EXPERIENCE AT A TERTIARY HOSPITAL > G. Gala Aglaia Mendez
Objectives : Describe the prevalence and specificity of IAs appearing in daily practice at a tertiary hospital.
Identify patients who develop additional IAs.
Take measures to avoid the appearence of Ias.
P-481 DIFFERENT TRANSFUSION STRATEGIES OF PATIENTS WITH MULTIPLE ALLOANTIBODIES OR ANTIBODIES TO HIGH-FREQUENCY ANTIGENS, AND WHO ARE UNDERGOING DARATUMUMAB TREATMENT > L. Livia VARGA P-482 AUTOMATED TITRATION OF BLOOD GROUP ANTIBODIES USING THE ORTHO VISION ANALYZER > K. Kristina RASMUSSEN
Objectives : Irregular antibodies
Automated titration
Validation
P-483 WHICH RED BLOOD CELL ANTIGENS ARE MOST IMMUNOGENIC IN CHILEANS? > M. Maria Antonieta NUNEZ
Objectives : Show that current immunogenicity estimates are not applicable to all populations.
Create awareness of the importance of studying erythrocyte antigens other than A, B and RhD.
To show that it is necessary to phenotype D antigen in Chilean donors and transfuse patients without this antigen.
P-484 INVESTIGATION AND ANALYSIS OF RHD(-)RED BLOOD CELL ADMINISTRATION IN GUANGZHOU BLOOD CENTER > W. Weifeng LUO P-485 CLINICAL AND SEROLOGICAL PROFILE OF ALLOIMMUNIZED AND AUTOIMMUNIZED MULTI-TRANSFUSED PATIENTS AGAINST RED BLOOD CELL ANTIGENS > S. Sudipta Sekhar DAS P-486 SOLID-PHASE RED CELL ADHERENCE VERSUS GEL COLUMN AGGLUTINATION: IS THERE ANY DIFFERENCE IN THE ANTI-JK ANTIBODIES DETECTION? > R. Roberto CUPAIOLO
Objectives : Anti-JK serology and the difficulties to detect them
Some anti-JK antibodies that are detected by SPRCA are not by the Coombs gel method
A lot of haemolytic transfusion reactions are linked to Kidd antibodies

P-487 A CASE OF MISTAKEN B: DISCOVERY AND EVALUATION OF A DONOR ABO MISTYPE > H. Heather PURCELL P-488 DEVELOPMENT OF AN INDEPENDENT READER SYSTEM THAT PARALLELS SIGNIFICANT STEPS OF FULL AUTOMATION CAPABILITY FOR IMMUNOHEMATOLOGY TESTING > T. Tony CASINA
Objectives : 1. Understand the contribution of manual interaction in error potential of testing and how increased automation impacts error potential
2. Evaluate how critical control points can be managed to mitigate error potential
3. Compare the concordance of two test systems and understand the results of the testing.
P-489 CHARACTERISTIC OF ANTI-LEWIS ANTIBODIES AMONG THAI BLOOD DONORS AND ITS CLINICAL SIGNIFICANT > J. Jairak THONGBUT
Objectives : 1. To investigate the prevalence of antibody screening positive in blood donors in Thai population
2. To investigate the antibody types identified from strongly positive antibody screening by CAT
3. To investigate the characteristic of anti-Lewis antibodies identified among strongly positive antibody screening (grading 3 and 4)
P-490 A PREGNANT WOMAN WITH NON-SECRETOR H-PARTIALLY DEFICIENT GENOTYPE AND OUTCOME OF HER NEONATE: A FIRST CASE REPORTED IN A TERTIARY HOSPITAL IN SINGAPORE > P. Pei Lun Karen LIM
Objectives : Sharing the First case seen in a pregnant woman
Journey through her pregnancy in Blood Bank's perspective
Important association with molecular and serologic results.
P-491 HIGH TITRE ANTI-A AND /OR ANTI-B TESTING OF DONORS IN THE REGIONAL BLOOD CENTER IN POZNAN IN THE YEAR 2019 > K. Katarzyna KOLASINSKA P-492 IDENTIFICATION OF SPECIAL RARE BLOOD TYPES IN THE SOUTH OF BRAZIL: IMPACT IN THE TRANSFUSION SUPPORT > C. Cristiane ARAÚJO
Objectives : Learn abou the creation of a database of rare blood types in the northern region of Rio Grande do Sul state, Brazil.
Knowing the rare phenotypes identified in both donors and patients.
Knowing if the phenotypes identified in this study are similar to other regions of Brazil and world.
P-493 ASSOCIATION OF POSITIVE DIRECT ANTIGLOBULIN TEST WITH NONREACTIVE ELUATE AND DRUG-INDUCED IMMUNE HEMOLYTIC ANEMIA > C. Cristiane ARAÚJO
Objectives : Knowing the association of positive DAT with non reactive eluate and drug-induced immune hemolytic anemia.
Knowing the percentage of antibody screening positivity in patients with DAT positive.
Knowing the drugs that the patients in this study were exposed.
P-495 PERFORMANCE OF ANTI-D REAGENTS OF GRIFOLS DG GEL CARDS WITH D VARIANT SAMPLES > J. Jordy Bozzo P-496 ABH ANTIGENS IN SEMEN OF YOUNG MEN WITH VARICOCELE > A. Adriana BRUFMAN P-497 IDENTIFICATION OF RARE S-S-U- BLOOD GROUP PHENOTYPE IN RHD NEGATIVE WOMAN: FIRST REPORT FROM INDIA > S. Swati KULKARNI P-498 CHALLENGES OF BLOOD COMPATIBILITY TESTING AND BLOOD TRANSFUSION IN PATIENTS TREATED WITH ANTI-CD38 MONOCLONAL ANTIBODY > M. Mirela RAOS
Objectives : 1. Develop knowledge of the mitigation methods to eliminate the anti-CD38 monoclonal antibody interference.
2. Understand the effectiveness of the mitigation methods to eliminate the anti-CD38 monoclonal antibody interference.
3. Learn how to select blood to ensure safe and timely transfusion to the patient with anti-CD38 monoclonal antibody.
P-499 CLINICALLY SIGNIFICANT ANTIBODIES IN PREGNANCY CAUSING HEMOLYTIC DISEASE OF THE NEWBORN > E. Emilija VELKOVA
Objectives : Immunohematology
Haemolitic Disease of the New Born
Red Blood Cells alloantibody in pregnancy
P-500 WARM AUTOIMMUNE HEMOLYTIC ANEMIA WITH AUTO ANTI-D AND ANTI-C SPECIFICITY > R. Rita POMBAL
Objectives : Description of clinical case
Elucidation of the immunohematological study
Discussion of the transfusion managing is such clinical cases
P-501 ONSITE EVALUATION OF TWO AUTOMATED BLOOD GROUPING ANALYSERS ZIMBABWE EXPERIENCE > G. George MAVUNGANIDZE P-502 PROSPECTIVE OBSERVATIONAL STUDY TO FIND THE PREVALENCE & TO SEROLOGICALLY CHARACTERIZE AUTOIMMUNE HEMOLYTIC ANEMIA (AIHA) PATIENTS IN A TERTIARY CARE TEACHING CENTRE > C. Cs CHIPPY
Objectives : Autoimmune hemolytic anemia (AIHA) is a clinical condition in which IgG and/or IgM bind to RBC surface antigens and initiate RBC destruction via complement & reticuloendothelial system. Although uncommon, it create challenges in providing safe blood adequately & timely. Appropriate immuno-hematology work up is often neglected in most of the blood banks due to time consuming procedures and, lack of expertise & facilities especially in rural areas. Unlike western countries, we lack knowledge of prevalence and characteristics of AIHA in our population. So we designed a prospective observational study after taking ethical approval from our institute to study the prevalence and to classify AIHA based on clinical and serological findings in our patient population in a period of six months at our hospital based transfusion medicine department.
Learning objective 1: To study the prevalence of AIHA in our population
Learning objective 2: To classify AIHA based on clinical & serological findings in our population
The findings may be helpful in framing the national policies regarding facilities and expertise needed to be ensured in blood centers all over the country as well as may highlight the need for a national reference laboratory for intensive immuno-hematology work up, rather than blind issuing of least incompatible blood units in case of challenging cases.
P-503 PREVALENCE OF DIEGO A ANTIGEN AND ANTIBODIES IN COLOMBIAN BLOOD DONORS: IMPLICATIONS IN TRANSFUSION MEDICINE > P. Paula Andrea GAVIRIA GARCÍA
Objectives : Know the prevalece of Dia antigen in Colombian blood donors
Know the prevalece of Dia antibodies in Colombian blood donors
discuss the clinical importance in tranfusion medicine


P-504 VALIDATION OF MAGISTER C24 WITH CELLBIND > L. Leonie VAN DER HEUL-NIEUWENHUIJSEN P-505 DETECTION OF IN-VIVO RED CELL BOUND PROTEINS (C3D) THROUGH MICRO-TITER PLATE AND AUTOMATED METHODS > N. Norkeshia BILLUPS P-506 COMPARATIVE STUDY OF ABO RH-KELL, REVERSE TYPING ANDEXTENDED PHENOTYPING REAGENTS ON THE BECKMAN COULTERPK7300 AND PK7400 AUTOMATED MICROPLATE SYSTEMS > F. Fanny DENIS
Objectives : -Knowing the difference between PK7300 and PK7400 reagents
-Knowing the tests performed to obtain the CE marking
-Knowing a new range of products available on the market in immunohaematology field
P-507 ANTOBODIES OF VARIANTS MNS IN THAI BLOOD DONOR > K. Kallaya KERDKAEWNGAM P-508 A CASE OF A D VARIANT WITH ALLO-ANTI D > I. Indika DE ALWIS P-509 FREQUENCIES OF ABO BLOOD GROUPS IN A CROSS SECTION OF PATIENTS – COMPARISON WITH FREQUENCIES IN HEALTHY SUBJECTS > K. Kristina RASMUSSEN
Objectives : ABO blood groups and alleles
Healthy donors, pregnant women and unselected patients
Morbidity and mortality
P-510 A UNUSUAL CASE OF SEVERE HEMOLYTIC REACTION CAUSED BY ANTI-LEA NOT DETECTED BY AUTOMATED METHOD > H. Harshita MEHROTRA
Objectives : Our case report highlights severe hemolytic transfusion reaction caused by anti-Le(a) which are considered clinically insignificant. Our patient had a history of anti-lewis antibodies which was not elicited as it was at a different institute. In this era of electronic records, this history must be recorded to ensure that these rare causes of hemolytic transfusion reactions are not missed.
P-511 FREQUENCY OF RED BLOOD CELL ANTIGENS AND RESPECTIVE ALLELES IN THE BLOOD DONOR POPULATION IN NORTHERN GREECE > G. Georgios KALTSOUNIS
Objectives : Calculating frequencies of antithetical RBC antigens and respective alleles using the Hardy-Weinberg equation
Frequencies of RBC antigens and respective alleles in the population of Northern Greece are consistent with literature reports regarding other populations of Caucasian origin
Blood donor screening for RBC antigens in the context of finding compatible units for patients that require extended phenotype matching
P-513 DAT NEGATIVE WARM AUTOIMMUNE HEMOLYTIC ANAEMIA IN A GIRL WITH HISTORY OF VIRAL INFECTION > V. Virginia OLIVENCIA PLAZA P-514 ANTIBODY SCREENING AND IDENTIFICATION IN DONORS AND GENERAL PATIENTS AT A TERTIARY CARE HOSPITAL > A. Abhinav VERMA
Objectives : 1.Antibody screening combined with phenotyping and identification should be done in all transfused patients and blood donors.
2.In our study antibodies against Rh and Kell blood group antigens were the most frequent amongst donors and general patient population requiring blood.
3.So we suggest that at least Rh and Kell matched blood should be given to all patients for safe blood transfusion and prevent alloimmunization.
P-515 DRUG-INDUCED IMMUNE HAEMOLYTIC ANAEMIA IN AIDS PATIENTS > C. Carlos GONZALEZ P-516 PREVALENCE AND SIGNIFICANCE OF RH & KELL ANTIGENS PHENOTYPING IN DONORS & PATIENTS: A RETROSPECTIVE ANALYSIS FROM A TERTIARY CARE ONCOLOGY CENTRE IN NORTH INDIA > A. Amardeep PATHAK P-517 THE ANALYSIS OF ABO BLOOD GROUP DISCREPANCIES AMONG THAI BLOOD DONORS > A. Apiwan PIPATVANICHKUL P-518 EVALUATION OF ERYTRA® FULLY AUTOMATED ANALYSER AT TRANSFUSION SERVICE - INDONESIA > E. Engla MERIZKA P-520 DIEGO B NEGATIVE PHENOTYPE IN THAI BLOOD DONORS > K. Kallaya KERDKAEWNGAM P-521 HUMAN MONOCLONAL ANTI-DI(A) SEROLOGIC TESTING > K. Kallaya KERDKAEWNGAM P-522 A CASE OF ANTI G + ANTI C - A SRI LANKAN PERSPECTIVE > I. Imali EDIRIWEERA P-523 FREQUENCIES OF RH & KELL ANTIGEN, IN THE POPULATION OF NATIONAL CAPITAL REGION > S. Sangeeta PATHAK
Objectives : 1.to provide antigen negative blood in immunized patients knowledge of antigen frequency is required
2.Antigen profile are useful in multitransfused patients
3.
P-524 INCOMPATIBLE CROSS MATCH DUE TO DIRECT ANTIGLOBULIN TEST POSITIVE DONOR UNITS: THE DILEMMAS FOR BLOOD CENTERS > P. Priti ELHENCE P-525 RESOLVING ABO DISCREPANCIES – MH04 CLONE AND THE MISSING A ANTIGEN > M. Maria Inês MOSER
Objectives : Study of ABO discrepancies

Characteristics of anti-A reagent MHo4
P-526 EVALUATION OF REACTIVITY OF VARIOUS MONOCLONAL ANTI-D REAGENTS WITH RED BLOOD CELLS OF INDIVIDUALS WITH INCONCLUSIVE RHD RESULTS > M. Monika PELC-KLOPOTOWSKA
Objectives : 1. Analysis of D antigen variants in Poland
2. Identification of RHD alleles in individuals with inconclusive test results
3. Effectiveness of serological methods to identify patients with weak D type 1, 2 and 3
P-527 POSSIBILITY OF WEAK D ANTIGEN DETECTION BY THE “SOLID PHASE” TEHNIQUE ON THE NEOIRIS AUTOMATIC SYSTEM > M. Milica DUKIC NOVAKOVIC P-528 IGM AND IGG ABO ANTIBODY TITERS: COMPARISON BETWEEN TWO METHODS > G. Giancarlo DE CAPRIO P-529 DELAYED HEMOLYTIC TRANSFUSION REACTION DUE TO ANTI-JKB IN A SICKLE CELL DISEASE PATIENT: A CASE REPORT > R. Romeu DUTRA
Objectives : Importance of a clinician capable to create an interconnection between clinical team at bedside and the technical staff.
Precaution in identification of a possible Kidd alloantibody, mainly in sickle cell disease patients.
Alloimmunization to Rh system, may be a predisposing factor to develop Kidd alloantibodies,
P-530 A SNAPSHOT OF ABO, RHD, RH PHENOTYPE AND KIDD PROFILE IN MODERN IRELAND > A. Anne BROWNE
Objectives : A snapshot of ABO, RhD, Rh phenotype and Kidd profile is presented for the Irish first time donor population for a specific time period.
Irelands population is becoming more diverse and this is indicated by the cohort of donors (14.24%), born outside Ireland, where aspects of the blood groups are statistically significantly different to the Irish born donors.
The population diversity has implications for the IBTS in its ability to provide blood products for certain cohorts of patients especially those with complex requirements. Many haemoglobinopathy and thalassemia patients require extended phenotyping due to regular transfusions and exchanges. Increased recruitment of donors from all ethnic backgrounds would be beneficial to the IBTS to improve its ability to meet all patient requirements.
P-531 PREVALENCE OF ABO AND RH BLOOD GROUP ANTIGENS IN DUBAI, UNITED ARAB EMIRATES (UAE) > N. Nazik HAMAD
Objectives : knowledge about the frequency of red blood cells ABO antigens in voluntary United Arab Emirates donors.
Knowledge about the frequency of Rhesus Blood antigens in voluntary United Arab Emirates donors.
Compare the frequency of ABO and Rh antigens in UAE donors with other countries in the region.
P-532 A STUDY OF ABO ANTIBODY TITERS USING THE MANUAL TITRATION AND TUBE METHOD COMPARED WITH TWO DIFFERENT AUTOMATED TITRATION AND MICROCOLUMN AGGLUTINATION METHODS > S. Sukanlayanee ONSEEDAENG P-533 PREVALENCE OF COLD AGGLUTININ IN TRANSFUSION PATIENTS IN A TEACHING HOSPITAL > J-H. Ju-Huei CHIEN P-534 INTEGRATION OF DONOR RED BLOOD CELL PHENOTYPING INTO THE BLOOD SUPPLY CHAIN > R. Rozi MUSA
Objectives : 1, The feasibility of simultaneously extended typing using Diagast Reagent via automation
2. Decrease in the average time to look for antigen negative blood.
3. Increase in the number of phenotyped donors
P-535 EFFECTIVENESS AND EFFICIENCY OF THE USE OF ALSEVER SOLUTION > S. Sandi AKBAR P-537 PATTERN OF ABO & RHESUS BLOOD GROUPS IN THALASSEMIA MAJOR PATIENTS. SNAPSHOT FROM A TERTIARY CARE CENTRE KARACHI > A. Ayesha MEMON P-538 ANALYSIS OF ANTIBODY SCREENING & IDENTIFICATION IN GENERAL PATIENT POPULATION USING A SOLID PHASE AUTOMATED METHOD > S. Sangeeta PATHAK
Objectives : 1.Rh & Kell are the most common antibodies in general patient population
2.SPRCA technology is a good method to detect all clinically significant antibodies
3.automated methods are recommended to detect these antibodies rather than the manual processes
P-539 RH PHENOTYPE, ABO AND KELL ANTIGENS, ALLELES AND HAPLOTYPE FREQUENCIES IN NORTH INDIAN BLOOD DONOR POPULATION > S. Sadhana MANGWANA
Objectives : 1. By knowing regional antigen frequencies, it would help to give transfusion support to alloimmunized patients.
2. Knowledge of varied frequency and phenotypic expressions of major clinically relevant antigens, would help in decreasing alloimmunization and thus enhancing blood safety.
3. Creating a Rare blood group registry and directing patients with antibodies against high-frequency antigens requiring multiple transfusions
P-540 PROFILE OF RHESUS ANTIGEN C AND E OF BLOOD DONORS IN BLOOD TRANSFUSION SERVICE DR. SARDJITO GENERAL HOSPITAL, YOGYAKARTA, INDONESIA > T. Teguh TRIYONO P-541 ANTI-ERYTHROCYTE ANTIBODIES DETECTED IN VOLUNTARY BLOOD DONORS AT INSTITUTE FOR TRANSFUSION MEDICINE OF FEDERATION OF BOSNIA & HERZEGOVINA > V. Vildana VILIC- HASANOVIC P-542 DETERMINATION OF THE RH PHENOTYPE IN VOLUNTARY BLOOD DONORS LIMA - PERU > S. Sergio ARIAS QUISPE
Objectives : 1. Provide information on the prevalence of Rh phenotype in voluntary blood donors in Lima - Perú.
2. Identify the most prevalent phenotype in our donors.
3. To provide tools for future studies that can relate migratory phenomena and their impact with the variation of the Rh phenotype of voluntary blood donors.
P-543 ENVIRONMENTAL INFLUENCES AND NATURAL SELECTION ON ABO AND RH (D) BLOOD GROUPS IN INDIAN SUBCONTINENT > Y. Yashaswi DHIMAN
Objectives : 1.Knowing the National ABO and RH Blood group distribution of the country
2.Calculating allelic and genotypic frequencies on national level and as well as region wise in the country
3.Observing the role of Natural selection and environmental influence of this distribution
P-LB-011 PREVALENCE OF RBC ALLOIMMUNIZATION AMONG BETA-THALASSEMIA AND SICKLE CELL ANEMIA PATIENTS IN AL-MADINAH REGION OF SAUDI ARABIA > A. Ahmed Alsharyufi
Objectives : To Identify the prevalence of RBC alloimmunization among beta-thalassemia and SCA patients in the Al-Madinah region of Saudi Arabia.
To Identify the most prevalent alloantibodies in the same patients.
To Identify the frequency of Rh and K antigens in the same patients.

Note: I registered at ISBT 2020 Virtual under Registration Identifier: ISBT 20BCN-1819
P-LB-012 FREQUENCIES OF DIFFERENT PATTERNS OF DIRECT ANTI-GLOBULIN TEST (DAT) IN PATIENTS WITH AUTOIMMUNE HAEMOLYTIC ANAEMIA AT TERTIARY CARE HOSPITAL IN KARACHI > R. Ruhul Quddus
Objectives : It is first study in our area describes the frequencies of different patterns of autoimmune haemolytic anaemia. Although due to logistic limitations DAT negative immune haemolytic anaemia couldn't be picked up and same was the case for mixed type AIHA (picked up by clinical history instead). Further studies in which separate classification mixed type AIHA based on clinical history plus laboratory workup and DAT-negative AIHA must be considered

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